The United States released 1,200 monkeypox vaccines in response to the outbreak

As part of these efforts, about 1,200 doses of the monkeypox vaccine have been administered in the United States, said Dr. Raj Punjabi, the White House’s senior director for global health security and biodefense.

“We want to ensure that people at high risk get vaccinations quickly, and if they get sick, they can receive appropriate treatment. So far, we have provided around 1,200 vaccines,” Punjabi said. “And 100 remedial courses in eight jurisdictions, and we have more to offer the states.”

Health care workers in Massachusetts treating monkeypox patients were among the first to receive vaccinations to protect them from the virus.

In the United States, the two-dose Jynneos vaccine is licensed to prevent smallpox and specifically to prevent monkeypox. Another smallpox vaccine licensed in the United States, ACAM2000, may also be used for monkeypox.

To date, more than 120 orthotopic PCR tests have been performed across the United States as part of outbreak surveillance.

“This is just a fraction of what is available,” Punjabi said, adding that 67 labs in 46 states – part of a network known as the Laboratory Response Network – have the “collective capacity” to perform more than 1,000 tests per day.

“So what we’re working on now is to ensure that the testing capacity is used,” he said. People with symptoms of monkeypox are encouraged to visit a healthcare provider, and providers are urged to test if they suspect someone has monkeypox.

There may be ‘community-wide’ spread, CDC official warns

Officials at the US Centers for Disease Control and Prevention on Friday urged doctors to look for potential monkeypox cases where the virus could spread to the community level.

Twenty cases of monkeypox have been identified in 11 states, plus another case in the United States that has been infected and tested elsewhere, said Dr. Jennifer McCuston, deputy director of the CDC’s Division of Pathogenesis and Pathology.

All patients recover or have recovered, and those who still have a rash are advised to stay home and isolate from others until they have fully recovered.

“I want to stress that this can happen in other parts of the United States,” McCuston said. “There may be community transmission going on, which is why we really want to increase our surveillance efforts.” “We want to really encourage clinicians that if they see a rash and they’re worried it might be monkeypox, to go ahead and get that tested.”

She added that the rash that appears as a result of monkeypox infection in this outbreak can be subtle and can be easily confused with other types of infection, especially sexually transmitted diseases – and there may be a co-infection of monkeypox with STIs.

The rash from monkeypox infection typically appears as “deep-rooted” and “well-rounded” lesions that develop into raised or fluid-filled blisters, McQueston said. She added that it could be confused with other infectious diseases such as herpes or syphilis.

“However, we don’t want to underestimate this condition,” McCuston said. “The rash caused by monkeypox virus can spread widely throughout the body or be present in sensitive areas such as the genitals.” “It can be really painful, and some patients have reported needing prescription pain relievers to control this pain. Sores can also cause long-term scarring on the skin.”

McQuiston said analysis of genetic sequence data from cases in the United States suggests that two genetically different types of monkeypox may be circulating.

The genetic sequence data is “certainly interesting from a scientific perspective,” but “to determine how long the monkeypox virus has continued to spread will require analyzing more sequences from a much larger number of patients to begin to piece together this puzzle more clearly,” she said. “It is certainly possible that there may be cases of monkeypox in the United States that have been under the radar before, but not to a significant degree.”

She added that the risk to the public remained low and that the discovery of cases with distinct lineages was a “positive sign” that the country’s surveillance network was working.

Anyone can get monkeypox, but the CDC warns the LGBTQ community not to
CDC researchers and health officials released a report Friday describing several cases of monkeypox in the United States, noting that “the ongoing investigation indicates community-to-person transmission, and the CDC urges health departments, clinicians, and the public to be vigilant.” and setting appropriate infection prevention and control procedures, and notifying public health authorities of suspected cases to limit the spread of the disease.”

Of the 17 cases described in the report across nine states, all patients developed a rash, 14 reported international travel in the 21 days prior to onset of symptoms, and all but one were identified as a man who had sex with men (MSM). Three of them are immunocompromised. All patients were adults.

“The high proportion of initial cases diagnosed in this outbreak in people who identify as gay, bisexual, or other MSM may simply reflect an early introduction of monkeypox into interconnected social networks; this finding may also reflect a confirmation bias due to Strong and well-established relationships between some MSM and clinical providers with strong STI services and extensive knowledge of infectious diseases, including uncommon ones,” the CDC researchers wrote in the report.

“However, infection is often not limited to certain geographic areas or population groups; because close physical contact with infected people can spread monkeypox, anyone, regardless of gender or sexual orientation, can acquire and spread monkeypox. .”

Globally, WHO officials say, more countries are reporting cases of monkeypox that have not seen the virus before.

“Cases have been reported in 26 countries” where the virus is not endemic, Maria Van Kerkhove, WHO chief for emerging and zoonotic diseases and technical advisor for Covid-19, said during a press briefing Thursday. She added that more than 600 cases have been identified in these countries.

“As monitoring increases, as interest increases, we expect to identify more cases,” she said. “Several investigations into the public health outbreak are underway.”

This outbreak is different from previous outbreaks because “we see all cases appearing in a relatively short period of time,” Rosamund Lewis, technical officer for monkeypox at the World Health Organization, said on Tuesday.

“What we’re seeing now started as a small group of cases, and then the investigation quickly led to an infection in a group of men who have sex with men, and that led to more investigations, so we haven’t yet identified the source of the actual outbreak.” “The most important thing now is not to stigmatize.”


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